Summer Intern/Immunogenicity
Department Description:
The Immunogenicity Department in Biomarkers and Bioanalytical Platforms provides analytical support and expertise for biotherapeutic programs in clinical development. Our scientists develop and validate clinical assays to detect and characterize immune responses that might arise against the biotherapeutics. Assays are validated and include ligand binging and cell-based platforms, informing potential impacts on drug pharmacokinetics, safety and efficacy.
Job Description:
We are looking for an intern to help us evaluate the impact of acid dissociation treatment on therapeutic and control antibodies in an immune complex model. We develop competitive ligand binding methods to identify neutralizing antibodies against our drugs using electrochemiluminescence readouts. In addition to these methods, the co-op would also use biochemical and biophysical characterization methods such as surface plasma resonance (SPR) and biolayer interferometry (BLI) to measure the interactions between the drug and the antibodies. The successful applicant would learn these techniques and more as we identify ways to study these interactions.
Minimum Qualifications:
- Pursuing a degree in Biology, Chemistry, Biochemistry, Bioengineering, or related disciplines.
- Must be able to work full-time (35-40 hours/week) throughout the 12-week assignment.
- Must have an active student status and/or within 12 months post-graduation from a BS or MS degree program. Post-doctoral candidates are not eligible.
Preferred Qualifications:
- Basic laboratory skills such as pipetting, solution preparation and pH measurement
- Willingness to learn and try new things
- Curiosity about how our bodies react to new medicines
Benefits:
- While GSK embraces a flexible work environment, we do require certain positions to be onsite. Candidates who are hired for an on-site or a hybrid role and reside outside of 50-miles from their assigned work location are eligible for relocation stipend. This is a one-time payment to help offset housing & relocation expenses. Please refer to the position details for the requirements of each position.
- GSK Interns and Co-ops are offered a competitive hourly pay rate and benefits. Please note, benefits eligibility to be determined upon hire.
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Eligibility Requirements:
- Must successfully pass a drug screen and background check prior to assignment target start date.
- If your skillsets are a match for this role, you will be contacted by our recruitment team with next steps to complete our internal World of GSK Assessment.
- Please note, you must receive a passing score to move forward in the interview process. Once your assessment is complete, a recruiter will review your results and be in touch with next steps.