We’re a global group that provides a deep scientific understanding of our drug candidates by applying a broad array of analytical techniques to evaluate and compare protein higher order structure at various points along the drug development process. The projects we impact span from early discovery to late phase III clinical trials. We unite state-of-the-art structural characterization science and diverse talent to enable informed decisions and develop transformational medicines for patients.
This position will allow the selected candidate to gain experience supporting analytical characterization of therapeutic proteins in all stages of clinical development within Medicine Development & Supply department located at our site in Collegeville, PA.
More specifically, the successful candidate will spearhead an initiative to evaluate and implement a protein tertiary structure quantitative comparison metric, which would be used in future monoclonal antibody drug filings to the FDA.
This position will involve hands-on training in the use of circular dichroism to evaluate mAb tertiary structure, training for the data analysis, and training for digital automation. The candidate will perform and document studies, evaluate data manually, write code to automate data evaluation, organize results, and present a recommendation to a forum of peers.
- Pursuing a Bachelor’s or Master’s degree in Chemistry, Biochemistry, Mathematics, or similar disciplines.
- Must be able to work full-time (35-40 hours/week) throughout the duration of the assignment.
- Must have an active student status and/or within 12 months post-graduation from a BS or MS degree program. Post-doctoral candidates are not eligible.
- Minimum 3.0 GPA.
- Experience coding in a programming language.
- Basic understanding of protein primary/secondary/tertiary structure, preferably of therapeutic proteins such as monoclonal antibodies.
- Experience evaluating new technology, methodology, or procedures either independently or under supervision.
- Experience with Circular Dichroism.
- Strong laboratory skills.
- Must successfully pass a drug screen and background check prior to assignment target start date.
- Must provide your own funding for relocation and commuting.
- If your skillsets are a match for this role, you will be contacted by our recruitment team with next steps to complete our internal World of GSK Assessment.
- Please note, you must receive a passing score to move forward in the interview process. Once your assessment is complete, a recruiter will review your results and be in touch with next steps.
If you are hired for an on-site role, you will be required to provide Atrium with proof of COVID-19 Vaccination as a part of the on-boarding process on behalf of GSK. GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical, or disability-related reasons.