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Spring Co-op/Upstream Biopharm Drug Substance

GSK
Description of Department:
Biopharm Process Development is a highly experienced Chemistry, Manufacturing and Controls (CMC) organization accountable for delivering robust, cost effective and competitive products and manufacturing processes spanning the full life-cycle of asset development from Discovery through commercialization. These activities are delivered through state-of-the art internal facilities as well as strategic external partners. Collectively, the team is accountable for CMC activities encompassing cell line development, cell culture/ microbial fermentation, purification development, and drug product/ device development. We also pioneer innovative technologies to improve robustness, reduce cost of goods, and improve the patient experience.
 
Within Biopharm Process Development, upstream scientists are responsible for the development of cell culture processes for the manufacture of GSK’s Biopharm assets. The department is also responsible for the scale-up and tech transfer of the processes to manufacturing facilities all over the world. Our aim is to integrate innovative expression and process platforms, automation and advanced data analytics into the upstream process development workflow.

Job Description:
An opportunity has arisen for a process development co-op. In this role, you will be a member of a highly skilled team of scientists and engineers responsible for development and optimization of cell culture and purification processes. The team will have access to the latest technology and analytical instruments. Although predominantly lab-based, the role also involves important aspects of verbal and written communication and requires good organization skills as well as a broad scientific knowledge. You will be working onsite within a matrix team and therefore the role will suit a scientist with good interpersonal skills, ability to solve complex problems, is self-motivated and has an open mindset.
 
As a Co-op, you will be working on the development and industrialization of the Capacitance technology, a process analytical technology used to measure the viable cell density of the cell culture in a bioreactor. You will help design and execute studies to evaluate the robustness and longevity of the capacitance probes and to provide recommendations on the use of the probes in a manufacturing facility. Toward this end, throughout the co-op the candidate is expected to:
  • Design and execute experiments.
  • Document experiments in an electronic notebook system.
  • Analyze and present data.
  • Write reports.

Basic Qualifications:
  • Pursuing a Bachelor's degree in Chemical Engineering, Biochemistry, Chemistry, Biology, or a related field.
  • Have basic laboratory experience.
  • Must be able to work full-time (35-40 hours/week) throughout the 6 month co-op.
  • Must have an active student status and/or within 12 months post-graduation from a BS or MS degree program. Post-doctoral candidates are not eligible.
  • Have a 3.0 or greater cumulative GPA.

Preferred Qualifications:
  • Ability to plan and execute experiments and to analyze and draw conclusions from resulting data.
  • Working knowledge of routine laboratory procedures (i.e., making solutions, pipetting, notebook documentation).
  • Excellent oral and written communication skills.
  • Ability to work with others and excel as a team member.
  • Strong learning agility.

Benefits:
  • GSK Interns and Co-ops are offered a competitive hourly pay rate and benefits. Please note, benefits eligibility determined the month following date of hire.

Eligibility Requirements:
  • Must successfully pass a drug screen and background check prior to assignment target start date.
  • If your skillsets are a match for this role, you will be contacted by our recruitment team with next steps to complete our internal World of GSK Assessment. Please note, you must receive a passing score to move forward in the interview process. Once your assessment is complete, a recruiter will review your results and be in touch with next steps.

If you are hired for an on-site role, you will be required to provide Atrium with proof of COVID-19 Vaccination as a part of the on-boarding process on behalf of GSK. GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons.